OmniGuide, Inc. is a U.S.-based medical technology company founded in 2000 and headquartered in Massachusetts. Originating from MIT research, the company specializes in advanced energy surgical systems, particularly flexible CO₂ laser technology. It is recognized for its hollow-core photonic fiber technology, which allows for precise energy delivery during minimally invasive surgery. OmniGuide serves various surgical fields including urology, ENT, gynecology, neurosurgery, and cardiothoracic surgery, with a strong focus on safety and tissue preservation.