Founded in 2010 following a public-private partnership based on the work of Professor Régis Logier and Dr Mathieu Jeanne, MDoloris Medical Systems is a French medtech company based in Loos, in the Lille region. Specialising in the development of non-invasive technologies for monitoring surgical stress and nociception, it is notably behind the Analgesia Nociception Index (ANI), a tool that continuously measures parasympathetic tone to help clinicians adjust pain management during anaesthesia and intensive care. A pioneer in this field, the company has also developed, in partnership with Mindray, an ANI-MR module compatible with BeneVision N Series monitors and validated by CE marking. Present in more than 70 countries, MDoloris has already installed several thousand devices worldwide, enabling hundreds of thousands of patients to benefit from its technological advances.