The 1260 Infinity (G4225A) Degassing Module for Accurate Analysis
The Agilent 1260 Infinity High Performance Degasser (G4225A) is an essential piece of equipment for laboratories using high-performance liquid chromatography (HPLC) systems. This vacuum degassing module is designed to effectively remove dissolved gases from solvents, a critical factor in ensuring accurate and reliable analytical results. Dissolved gases, such as oxygen and nitrogen, can cause flow instabilities, baseline noise, and even sample degradation, compromising the quality of analyses. The G4225A addresses these challenges by integrating state-of-the-art technologies and an optimised design for maximum performance.
At the heart of the G4225A are four separate vacuum chambers equipped with semi-permeable tubing. When the module is activated, a vacuum pump generates low pressure in these chambers, allowing dissolved gases to permeate through the tubing and be removed. This process is controlled by a pressure sensor and a sophisticated regulation system, ensuring constant and efficient degassing. The module is also equipped with an air filter to maintain stable pressure in the vacuum chambers while preventing excessive leaks.
The integration of the G4225A into an HPLC system is simplified thanks to its flexible connections and compact dimensions. It can be easily stacked with other Agilent 1260 Infinity modules, optimising workspace while minimising dead volumes in the system. The module is compatible with a wide range of solvents, including organic and aqueous solvents, and can handle flow rates of up to 10 mL/min per channel.
The G4225A is particularly useful for applications requiring high sensitivity, such as those using low-wavelength UV detectors, fluorescence detectors, or LC-MS systems. It is also essential for analyses requiring maximum precision in retention times and peak areas, as well as for low-flow applications where the effects of dissolved gases are amplified.
The G4225A is designed for easy maintenance. The most frequently replaced components, such as fuses and covers, can be exchanged by the user without the need for specialised tools. The module is also equipped with leak sensors and waste management systems to ensure safe and clean operation.
The Agilent 1260 Infinity High Performance Degasser (G4225A) is an essential tool for laboratories seeking to improve the quality of their HPLC analyses. With its design, compatibility with a wide range of solvents, and ease of integration, it offers a complete solution for removing dissolved gases and ensuring reliable and accurate analytical results.
