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Automated Nucleic Acid Purification System MagNA Pure 96 - Fair Condition

Brand: Roche


The MagNA Pure 96 from Roche is an automated nucleic acid purification system capable of processing up to 96 samples in less than one hour. Designed to meet the demands of high-throughput laboratories, it uses proven magnetic bead technology to extract DNA, RNA, and viral nucleic acids from a wide range of biological matrices. With pre-filled reagents, an intuitive interface, and pre-programmed protocols, it ensures reproducible results while significantly reducing human error. The MagNA Pure 96 enhances productivity while providing full traceability of operations.

Description

MagNA Pure 96: Reliable Performance for High-Demand Laboratories

The MagNA Pure 96 from Roche is an automated nucleic acid purification system designed for laboratories handling high volumes of extractions while maintaining strict precision and consistency in results. Capable of processing up to 96 samples in parallel, it features two distinct robotic arms, enabling efficient and uniform processing with hands-on time reduced to less than 5 minutes. Extraction is based on proven glass magnetic bead technology, trusted for over 20 years for its reliability.

Its applications span a broad range, including genomic DNA, total RNA, viral DNA/RNA, and circulating cell-free nucleic acids (cfNA), extracted from a variety of sample types such as whole blood, plasma, FFPE tissues, respiratory specimens, and cell cultures. Pre-filled and barcoded reagent kits ensure complete traceability throughout the workflow, minimizing errors and meeting regulatory compliance requirements.

The system offers a wide selection of preloaded protocols tailored to common sample types encountered in both research and diagnostic settings. It delivers nucleic acid extracts ready for downstream applications such as real-time PCR, microarrays, and next-generation sequencing. One of the key strengths of the MagNA Pure 96 lies in its outstanding reproducibility, with a coefficient of variation (CV) below 2% for both intra- and inter-run performance.

Its graphical user interface guides operators step-by-step, from sample preparation to extraction launch. Built-in features such as error detection, volume monitoring, and deck control further enhance process security and reliability. In addition, integrated contamination prevention mechanisms—including a UV lamp, droplet catcher, and secure-fit pipette tips—help maintain result integrity.

The MagNA Pure 96 integrates seamlessly into modern laboratory workflows, offering LIMS compatibility, standardized data export options, and comprehensive user management. Its scalability, combined with consistently reliable results, makes it an ideal solution for high-throughput environments such as hospital laboratories, research facilities, and molecular biology labs.

Features

  • Automated magnetic bead-based extraction
  • Ready-to-use, barcoded reagents
  • User-friendly software with real-time error detection
  • Reproducible extractions and reliable inter-batch results
  • Optimized protocols for various sample types
  • Compatible with qPCR platforms (e.g., LightCycler® 480)

Technical Details

  • Format: Standalone benchtop instrument with separate control unit
  • Throughput per run: 1 to 96 samples
  • Sample volume: 50 µL to 1 mL (up to 4 mL for plasma)
  • Elution volume: 50 to 200 µL
  • Run time: Approximately 50 to 90 minutes
  • Hands-on time: Approximately 5 minutes
  • Traceability: 21 CFR Part 11 compliant, audit trail, operator guidance
  • Data export formats: .xml, LightCycler® input files (.txt)
  • Connectivity: USB, LAN, LIMS via HL7 protocol, remote service via Axeda
  • Dimensions (W x D x H): 136 x 81.5 x 100 cm
  • Weight: 235 kg
  • Robotic head: Dual-arm system for parallel liquid and sample transfer
  • Contamination control: UV lamp, droplet catcher, CO-RE tips

Compatible Accessories

  • MagNA Pure 96 Processing Cartridges
  • MagNA Pure 96 Output Plates
  • 1000 µL Filter Tips
  • MagNA Pure Sealing Foils
  • Internal Control Tubes
  • Internal/External System Fluids
  • Specific Lysis Buffers (e.g., cfNA Buffer Set, Bacterial Lysis Buffer)

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