Agilent G1375-87304 capillary: the precision connection solution for capillary LC systems
The Agilent G1375-87304 capillary is an essential component for laboratories using capillary or nano-flow liquid chromatography systems. Designed specifically to integrate seamlessly with the 1200 series autosamplers, including the G1377A Micro Well Plate Autosampler, this capillary ensures optimal performance for applications requiring very low dispersion and minimal dead volume.
This capillary is made from two benchmark materials in the analytical field: PEEK (polyetheretherketone) and fused silica. This unique combination brings together the mechanical flexibility of PEEK and the chromatographic properties of silica, such as low adsorption and excellent chemical resistance. With an internal diameter of 50 microns (0.05 mm), this capillary is perfectly suited to low injection volumes, typical of capillary or nanoLC applications.
Its length of 500 mm ensures optimal connectivity between LC system components while maintaining a minimal connection volume, thus limiting sample dilution and improving chromatographic resolution. Another major advantage of the G1375-87304 is its fitting configuration: two PEEK Microvalve (MLP) fittings at one end (M4, ID 0.8 mm, long version) and a PEEK 10-32 WF (Winged Finger-tight) fitting at the other end. All these fittings are non-swaged, making them easy to install and replace without specialised tools.
The G1375-87304 is fully compatible with capillary liquid chromatography techniques, particularly for analyses where dead volume control and connection stability are essential. It is used in configurations where high injection accuracy is required, particularly with the microvolume injectors fitted to G1377A autosamplers. It can be integrated into a robotic sampling and injection system allowing sample volumes in the order of nanolitres to a few microlitres, while maintaining an extremely low level of dispersion.
The G1375-87304 is recommended for laboratories requiring perfect injection repeatability, maximum cross-contamination reduction and high mechanical and chemical stability. Its role in the overall analytical circuit is crucial, particularly in ensuring perfect sealing under pressure conditions of up to 400 bar, which are characteristic of modern capillary systems.
