Sartobind® Q SingleSep 5": High-Capacity Chromatography for Scalable Biopharmaceutical Processing
The Sartobind® Q SingleSep 5" is a state-of-the-art ion exchange chromatography capsule, designed to meet the demands of the biopharmaceutical industry for intermediate and large-scale purification processes. This single-use device simplifies the purification of proteins and other biomolecules through its advanced macroporous membrane technology, which allows for efficient binding and separation of target molecules.
With a membrane volume of 70 ml and an area of 2500 cm², the Sartobind Q SingleSep 5" is specifically engineered to handle larger sample volumes and support scaling from pilot production up to full-scale manufacturing. The macroporous membranes are functionalized with ion exchange ligands, offering a high dynamic binding capacity of 2.0 g per device. This makes it particularly suitable for the downstream processing of proteins and other biotherapeutic compounds, allowing biomanufacturers to achieve high throughput and purity in a single, streamlined step.
One of the key advantages of the Sartobind Q SingleSep 5" is its ease of use. Traditional chromatography often involves complex setups and requires extensive time and maintenance. However, this capsule integrates all the necessary components for rapid operation in a compact, single-use format. The membrane is fitted into a durable plastic housing that provides structural integrity and sanitary operation, while the silicone gaskets ensure secure connections to the chromatography system. This single-use design reduces the need for cleaning, validation, and maintenance, making it ideal for industries where minimizing downtime and contamination risks is crucial.
The Sartobind Q SingleSep 5" operates with a recommended flow rate of 1.9 L/min, making it capable of handling high-volume processes without compromising on efficiency or binding capacity. Additionally, the flushing volume of 2.5 liters ensures that the membrane is thoroughly cleaned during operation, which helps maintain its performance across multiple runs.
For laboratories and manufacturing facilities focused on scaling their operations, the Sartobind Q SingleSep 5" provides a seamless transition from small-scale experimentation to full-scale production. The device is designed with scalability in mind, with the same robust technology applied across a range of capsule sizes to suit different volume requirements. It can be used in various downstream processing applications, including the purification of monoclonal antibodies, recombinant proteins, and viral vectors.
The Sartobind Q SingleSep 5" combines high binding capacity, ease of use, and scalable performance, making it an essential tool for biopharmaceutical manufacturers looking to optimize their downstream processing.
