DAWN HELEOS II Macromolecular Characterisation Instrument

DAWN® HELEOS® II: Multi-Angle Light Scattering Instrument for Macromolecular Characterisation

The DAWN® HELEOS® II is a state-of-the-art instrument in the field of macromolecular characterisation, recognised worldwide for its multi-angle light scattering (MALS) capabilities. This device is specially designed to provide absolute characterisation of proteins, conjugates, macromolecules and nanoparticles, making it an indispensable tool for research laboratories and industrial applications. Thanks to its static multi-angle light scattering technology, the DAWN® HELEOS® II can accurately determine the molar mass and size of macromolecules and nanoparticles in solution.

One of the most remarkable features of the DAWN® HELEOS® II is its exceptional sensitivity , which allows it to detect very low concentrations of macromolecules. This, combined with a wide range of molecular weights, sizes and concentrations, makes this instrument a versatile choice for a variety of applications. Whether for fundamental research or industrial product development, the DAWN® HELEOS® II offers unrivalled performance.

The DAWN® HELEOS® II is often used in conjunction with chromatography techniques such as gel permeation chromatography (GPC-MALS), size exclusion chromatography (SEC-MALS) or field flow fractionation (FFF-MALS). These combinations allow the mass, size and composition distributions of samples to be determined without relying on column calibration with reference standards, thus providing more accurate and reliable results.

Another major advantage of the DAWN® HELEOS® II is the inclusion of ASTRA software, recognised as the most versatile software package available for online multi-angle dynamic light scattering analysis. ASTRA allows users to process and analyse data efficiently, facilitating the interpretation of results and informed decision-making.

The DAWN® HELEOS® II is a high-tech macromolecular characterisation instrument that offers unrivalled sensitivity and versatility. Its use in conjunction with chromatography techniques and ASTRA software makes it an indispensable tool for researchers and scientists working in various fields, including biochemistry, polymer science and nanotechnology. With its exceptional performance, the DAWN® HELEOS® II continues to set the standard in macromolecular characterisation.

• Molecular weight range: 200 Da to 1000 MDa
• Sensitivity: 0.4 µg/mL BSA (66.4 kDa)
• Size range: 10 to 500 nm, up to 1000 nm with specific shape models
• Ultra-stable, high-power laser