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Dionex ICS-5000 ion chromatography system

The Thermo Scientific Dionex ICS-5000 is a modular high-pressure ion chromatography (HPIC) system designed for fast, accurate and reproducible analyses. It incorporates features such as reagent-free eluent generation, exceptional baseline stability and the ability to operate in capillary, microbore or standard formats. With its configurable modules and ability to maintain pressures up to 5000 psi, it meets today's analytical needs while anticipating future challenges. The system is controlled via Chromeleon software for complete control and simplified data management.



Description

The Thermo Scientific Dionex ICS-5000: precision, modularity and continuous performance

The Dionex ICS-5000 from Thermo Fisher Scientific is a modular ion chromatography system capable of operating at high pressure for fast, reproducible analyses. It stands out for its ability to combine capillary (0.2–0.6 mm internal diameter), microbore (1–3 mm) and standard (3–7 mm) formats, with a flow range of up to 10 mL/min in analytical format. This flexibility allows the system to be easily adapted to various applications without increasing the footprint on the bench.

Designed to withstand up to 5000 psi with eluent generation, it guarantees finer separations through the use of 4 µm particle columns. Its Reagent-Free™ eluent generation module ensures ultra-pure eluent production directly from deionised water, reducing variability and contamination risks. Thanks to "Just Add Water" technology, operation is guaranteed for several months in the capillary with only two litres of water.

The DC Detector/Chromatography module organises separation, detection and automation, offering up to six independent thermal zones. This precise temperature management improves baseline stability and optimises the sensitivity of the conductivity detector and electrochemical detector.

The system also offers dual pumping capability (SP Single Pump and DP Dual Pump), allowing two types of analysis (e.g., anions and cations) to be performed simultaneously with a single piece of equipment. The internal construction of inert materials (PEEK™) ensures full compatibility with a wide range of eluents and solvents across the entire pH range.

Controlled via Chromeleon™ software, the Dionex ICS-5000 simplifies method configuration, data acquisition and system diagnostics. System Wellness features prevent failures by alerting the user to potential problems.

The system is scalable: it can be configured with optical detectors, additional modules for automation, or IC Cubes for capillary consumable management. This modularity allows laboratories to maintain high productivity while ensuring the reliability and quality of their analyses over the long term.

Features

  • Reagent-Free™ system with integrated eluent generation to reduce manual preparation and improve reproducibility
  • Precise thermal management with up to six simultaneously controlled temperature zones
  • Modularity allows the addition of IC Cube™, automation via Automation Manager, or optical detection
  • Multi-mode detection: conductivity, electrochemistry, UV-Vis absorbance
  • Centralised control via Chromeleon™ for all functions: pump, temperature, detection, diagnostics
  • Dual piston pump in series ensures stable and quiet flow
  • Wellness system for predictive maintenance based on usage
  • Adaptability to standard, microbore and capillary columns on a single platform

Technical Details

  • Maximum pressure: 5000 psi (analytical), 6000 psi (capillary without eluent generation)
  • Flow rate: 0.001–10.000 mL/min (analytical), 0.001–3.000 mL/min (capillary)
  • Flow accuracy: < 0.1%
  • Flow accuracy: < 0.1%
  • Generated eluent concentration range: 0.1–100 mM (analytical), 0.1–200 mM (capillary)
  • Chemical compatibility: pH 0–14, reverse phase solvents accepted
  • Construction materials: PEEK™ pump head, fully polymer flow path
  • Main module dimensions: 41 × 23 × 56 cm
  • Weight: SP (20.4 kg), DP (24.1 kg)

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