G1316-80003 Downstream Heating Device: Optimised Thermal Stability for Sensitive Medical Analyses
Agilent's G1316-80003 downstream heating device integrates with the column compartments of the G1316B SL and G1316C SL Plus models to ensure precise heating of the segments downstream of the chromatography column. This technical component, although discreet, plays a crucial role in maintaining the thermal integrity of samples until detection, particularly in biomedical analyses where reproducibility is essential.
With an internal diameter of 0.12 mm and an internal volume of only 1.6 µl, the G1316-80003 effectively limits dead volume while ensuring fast and uniform heat transfer. This level of control stabilises the temperature of solutes immediately after they exit the column, reducing thermal variations that could affect the accuracy of results.
Used in high-performance liquid chromatography (HPLC) systems, this device is particularly suitable for medical environments, where stable analytical conditions are essential for reliable diagnostics or pharmaceutical quality control. Its low volume also reduces thermal dispersion effects, improving resolution and limiting band broadening, two critical criteria in analytical chromatography.
The G1316-80003 is compatible with the G1316B SL/G1316C SL Plus capillary kit, in addition to devices such as the upstream heater (G1316-80002) or the post-column cooler (G1316-80004). These components can be fixed in specific locations in the column compartment using dedicated brackets (G1316-83200), ensuring stable installation that complies with laboratory requirements.
This device thus contributes to the overall accuracy of the chromatography system by providing additional thermal stability where it is most often overlooked: at the column outlet. Paying particular attention to this detail optimises the entire analytical system, making results more reliable, especially in critical medical analyses where every variation can have an impact on interpretation.
