F2402H – A high-performance, safe solution for centrifuging small biological volumes
The Beckman Coulter F2402H rotor is a high-performance centrifugation solution specifically developed for the demanding needs of research and diagnostic laboratories. Thanks to its hermetically sealed design, this rotor guarantees maximum safety when handling potentially pathogenic or sensitive samples. It is designed to fit a wide range of Beckman Coulter centrifuges, including the Allegra 64R, Avanti 30, Allegra X-30, X-22, 21 Series, GS-15 and Spinchron 15 models, ensuring versatility of use in multiple environments. This fixed-angle rotor is inclined at 45 degrees to the axis of rotation, allowing rapid and efficient sedimentation of biological particles, including cell organelles, viruses, bacteria, mitochondria, chloroplasts and algae.
The F2402H can hold up to 24 tubes of 1.5 to 2.0 mL, or smaller microtubes via adapters, with a maximum capacity of 48 mL per cycle. It reaches a rotation speed of up to 26,000 rpm in an Allegra 64R or Avanti 30, generating relative centrifugal forces (RCF) of up to 61,970 × g. The speed varies depending on the centrifuge model used, ensuring optimal adaptation to each equipment configuration. This rotor has a locking screw fastening system and a lid with a double O-ring seal to ensure the necessary tightness for protection against microbiological aerosols. Validated by third-party testing (CAMR or USAMRIID), this system is certified to effectively contain biological agents under normal operating conditions.
In terms of manufacturing, the F2402H rotor is made of anodised aluminium, a material that is resistant to corrosion and wear. Maintenance is easy thanks to the simple disassembly of components, and it is compatible with a wide range of cleaning and disinfection products, including ethanol, hydrogen peroxide and specific solutions such as RadCon. Regular cleaning and inspection of the O-rings is recommended to ensure optimal and long-lasting performance. In the event of biological or radioactive contamination, the rotor can be decontaminated according to current procedures and then autoclaved at 121°C for one hour.
This rotor is perfectly suited to a wide range of common laboratory applications: sample preparation for biomolecular analysis, cell fraction isolation, virus purification, or gradient centrifugation. It stands out for its compact size, fast speed ramp-up and ramp-down, and its ability to process a large number of small-volume samples simultaneously. Its robustness and safe design make it a strategic choice for laboratories seeking efficiency, versatility and safety.
