FAIMS Pro Duo Spectrometry Interface

FAIMS Pro Duo Interface: Selectivity and Flexibility for Mass Spectrometry

The FAIMS Pro Duo interface from Thermo Fisher Scientific represents a major advance in mass spectrometry, offering unmatched selectivity and flexibility for qualitative and quantitative analyses. This innovative technology overcomes the challenges posed by sample complexity and matrix interference, while reducing the need for time-consuming sample preparation.

FAIMS Pro Duo uses high-asymmetric field differential ion mobility spectrometry ( FAIMS) to introduce orthogonal selectivity into your existing workflows. This approach increases sample coverage, extends the quantitative dynamic range and broadens research opportunities. The interface is compatible with a wide range of Thermo Scientific mass spectrometers, including the Orbitrap and TSQ series, making it versatile for a variety of applications, from small molecules to intact proteins.

One of the key advantages of FAIMS Pro Duo is its ability to perform online gas phase fractionation, minimising the time, costs and variability associated with offline fractionation methods. By adjusting the compensation voltage (CV) and electrode temperature parameters, users can modify ion transmission to achieve their experimental goals. This flexibility optimises the detection and quantification of analytes of interest, while improving workflow robustness.

The FAIMS Pro Duo interface is also designed to be easy to install, use and maintain. Its unidirectional assembly and  installation without breaking the instrument vacuum simplify cleaning and maintenance routines. In addition, uniform and simple calibration routines ensure optimal usability and high-quality data acquisition, even for users of all skill levels.

By integrating the FAIMS Pro Duo interface into your mass spectrometry workflows, you can improve the analytical performance of your LC-MS methods, increase sample coverage and expand research opportunities. Whether for proteomics, biomarker discovery or other analytical applications, the FAIMS Pro Duo offers a powerful and versatile solution to meet your experimental needs.

• Power supply: 100-240 VAC 50/60 Hz 2.0 A, with no voltage variations outside the recommended operating range.
• Gas: 99.5% purity nitrogen, ≥ 20 L/min (100 psi).
• Operating temperature range: 15-32°C (59-90°F)
• Optimal temperature range: 18-27°C (65-81°F)
• Dimensions: 483 x 318 x 64 mm (h x w x d - 19 x 12.5 x 2.5 inches)
• Weight: 3.7 kg (8.2 lb)