Agilent G1376A: high-precision liquid chromatography capillary pump
The Agilent G1376A capillary pump is designed to meet the requirements of laboratories specialising in ultra-low flow liquid chromatography. It is based on a two-channel independent architecture, each equipped with two pistons in series, allowing for precise and stable solvent delivery. The electronic flow control system, combined with an electromagnetic proportioning valve (EMPV), ensures dynamic regulation of the flow to the column, while eliminating variations related to pressure or the nature of the solvents.
The internal configuration of the pump allows rapid gradients to be generated across the entire composition range, with reduced dead volume thanks to optimisation of the hydraulic path. The mobile phases are mixed in a static tube filled with stainless steel balls, ensuring constant homogeneity. The flow sensor, based on mass thermal sensitivity, provides reliable measurement calibrated according to the solvents used.
Modular design and simplified maintenance
The G1376A incorporates Agilent's E-PAC concept, combining layers of EPP foam for shock absorption and internal electromagnetic shielding. This design facilitates access to components for maintenance while reducing radio interference. The module also features an Early Maintenance Feedback (EMF) system, which tracks seal wear and solvent volume pumped, with customisable thresholds for planning maintenance.
The pump is compatible with Agilent control software (ChemStation, EZ-Chrom, OL) and offers several communication interfaces: CAN, RS-232C, LAN and APG Remote. It can be integrated into single or dual stack configurations, with optimised connectivity for other modules in the 1200/1260 Infinity series.
Performance and compliance for regulated environments
The G1376A is designed to operate in environments subject to strict standards such as GMP, ISO and FDA. It incorporates diagnostic, leak detection, compressibility compensation and automatic calibration functions. Its operating pressure range is 20 to 400 bar, with a flow accuracy of less than 0.7% RSD. The module is equipped with stainless steel filters, fused silica capillaries and components resistant to aggressive solvents, ensuring optimal durability.
With its robust design, dispensing accuracy and tracking capabilities, the G1376A is a strategic choice for laboratories seeking to control their capillary flows while complying with regulatory requirements.
