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G2258A Sampler - Good Condition

The Agilent G2258A is a dual-loop automatic sampler designed for preparative and analytical HPLC applications requiring fast injection of high volumes. Featuring two pre-installed sampling loops, it allows easy switching between analysis scales without hardware modification. This system improves injection flexibility and accuracy while minimising the risk of cross-contamination thanks to needle rinsing and washing functions. Ideal for purification laboratories, it integrates seamlessly with the 1200 series LC systems.



Description

Agilent G2258A: A Versatile Automatic Sampler for Preparative and Analytical HPLC

Agilent's G2258A automatic sampler, part of the 1200 series, has been specially designed to meet the needs of high-performance liquid chromatography (HPLC) applications in preparative mode. Its dual-loop architecture offers a solution that maximises flexibility and productivity while ensuring high-level analytical performance.

One of the major advantages of the G2258A is its ability to handle two sampling loops of different volumes, allowing for seamless switching between preparative and analytical analyses without having to physically replace components. This saves considerable time in high-throughput laboratories and minimises the risk of human error.

Operation is based on a fixed loop injection system combined with an external dosing syringe that is not directly integrated into the solvent circuit. This configuration allows precise injection of the desired volume, while reducing cross-contamination thanks to an automatic needle rinsing and washing system. The entire sample path can be effectively purged using suitable solvents, significantly reducing carryover to less than 0.1%.

The G2258A offers two injection modes: partial loop filling and full loop filling. Partial filling is ideal for limited samples, while full filling, with a configurable overfill factor, ensures excellent peak area accuracy, particularly useful for rigorous quantifications. These options are easily configurable via Agilent ChemStation software.

Compatible with a wide variety of well plates, vials and Eppendorf tubes, the G2258A allows flexible sample loading. A thermostatic module (ref. G1330B) can also be added to maintain samples at a controlled temperature between 4 and 40°C.

Robust, reliable and intuitive, the G2258A automatic sampler is an essential tool for any preparative purification or analytical research laboratory requiring reproducible, high-precision injections. Its modular design, compatibility with flow rates up to 100 ml/min, and integrated diagnostic and maintenance functions make it a strategic choice for HPLC applications.


Features

  • Automatic switching between two loops (analytical and preparative)
  • Compatible with Agilent ChemStation, Instant Pilot, HT Purification Software
  • Needle washing via dedicated port with peristaltic pump
  • Carryover reduction < 0.1% thanks to efficient rinsing
  • Polarity indicators to prevent connection errors
  • Maintenance and error logging (GLP-ready)
  • Rinsing solvent level monitoring
  • Supports organic solvents and water-solvent mixtures
  • Integrated leak detection system
  • Loop and filling mode selection via software
  • Compatible with samples of viscosity 0.2–5 cp

Technical Details

  • Loop type: Fixed double loop with 10-port valve
  • Injection volume range: 0.1 µL to 5000 µL (0.1 µL increments)
  • Injection modes: Full and partial filling
  • Sampling/ejection speed: Up to 50 mL/min
  • Maximum loop size: 5 mL (selectable range: 5 µL to 50,000 µL)
  • Surface accuracy (full loop): < 0.5% RSD
  • Surface accuracy (partial loop): < 1.0% RSD
  • Sample capacity: 2 plates (wells, vials, Eppendorf) + 10 vials of 2 mL
  • Operating temperature: 4 to 55 °C
  • Temperature (thermostated module): 4 to 40 °C
  • Weight: 14 kg
  • Dimensions: 200 x 345 x 440 mm
  • Power supply: 100–240 VAC, 50/60 Hz
  • Power: 200 VA max.
  • Connectivity: CAN, RS232C, APG remote, optional: LAN
  • Compliance: IEC, CSA, UL (indoor use only)

Compatible Accessories

  • Accessory kit G2258-68705, including:
    • Front/rear ferrules 1/16" (stainless steel)
    • Vial plates: 54 x 2 mL and 15 x 6 mL
    • Flexible capillary tubes (0.25 mm and 0.5 mm x 800 mm)
    • CAN cable 1 m
    • Wrenches (1/4", 5/16", 4 mm)
    • Hexagonal screwdrivers (2 mm, 3/32")
    • Air channel adapter
    • ESD antistatic strap
    • Flush kit (tubes, plugs, etc.)
  • Thermostat module (optional G1330B) with cable and specific kit
  • Compatible plates and vials:
    • 96-well plates (shallow, deep, conical)
    • 2 mL, 6 mL vials
    • 0.5, 1.5, 2.0 mL Eppendorf tubes
    • Max. plate height: 50 mm (with tray G2258-60001)

Logistics

Remma and its partners provide you with serviced and configured equipment tailored to your needs. Receive your product at your facility with standard or express delivery, and an installation option, all through a single point of contact.

Warranty

Our 12/24-month warranty ensures the safety and reliability of your medical equipment throughout its lifespan.

Flexible Financing

Settle your medical equipment in up to 36 installments with our financing service or pay after delivery with Remma Facility.