BLItz Label-Free Protein Analysis System for Real-Time, Drop-Based Quantification and Kinetics
The Pall ForteBio BLItz™ Label-Free Protein Analysis System is a compact, benchtop device that revolutionizes protein analysis by making label-free technology accessible at the individual researcher's bench. Powered by Bio-Layer Interferometry (BLI), the system enables real-time detection and quantification of biomolecular interactions in seconds—without the need for labels, secondary reagents, or complex sample preparation.
With only a 4 µL drop of sample, researchers can instantly monitor binding kinetics, protein presence, and concentration, even in crude or complex mixtures. This provides a significant edge over traditional methods such as Western blots and ELISAs, which often require extensive workflows and extended timelines. The BLItz system's ability to deliver actionable data in real time supports better decision-making in drug discovery, assay development, and protein engineering.
The key strength of the BLItz system lies in its versatility. Whether quantifying recombinant protein yields, screening antibodies, optimizing assay conditions, or characterizing affinity constants (ka, kd, KD), BLItz allows researchers to perform precise assays right from the lab bench. The accompanying BLItz Pro software simplifies experiment design, execution, and analysis, guiding users through kinetic evaluations and quantification workflows with minimal learning curve.
Built with a rugged yet compact design, the BLItz system requires minimal space, fitting easily into even the most crowded laboratory settings. This, combined with its affordability and minimal maintenance requirements, makes it ideal for academic labs, biotech startups, and quality control environments alike.
An extensive array of ready-to-use Dip and Read™ biosensors adds to the flexibility of the system, covering a wide range of assay targets and surface chemistries—from general-purpose (e.g., Ni-NTA, Protein A, Streptavidin) to application-specific biosensors (e.g., Anti-Human Fab-CH1, Anti-GST). Each biosensor is designed to deliver high sensitivity and reproducibility across a broad dynamic range, supporting both low- and high-affinity interactions.
The BLItz system enables researchers to not only see what binds, but how and how strongly, all in a matter of minutes. This rapid access to detailed binding data empowers more efficient research cycles and more confident decisions in the early stages of discovery.