FUJIFILM LAS-3000 Luminescent Image Analyser: an imaging platform for life science research
The FUJIFILM LAS-3000 is a high-performance imaging system specially designed for the detection of chemiluminescent and fluorescent signals in molecular biology and biochemistry applications. With its 3.2-megapixel Super CCD sensor, it offers high native resolution of up to 6.3 million pixels through software processing, enabling accurate visualisation and rigorous quantification of signals. The system features advanced technologies such as dark and flat-field correction, ensuring maximum accuracy in image data analysis.
The LAS-3000 combines multiple light sources for optimal flexibility: transmitted UV light at 312 nm, blue incident light (460 nm), and optional green (520 nm) and red (630 nm) LEDs. This variety of sources enables the effective detection of a wide range of fluorochromes, such as SYBR Green, EtBr, SYPRO dyes, Alexa Fluor and many others. Thanks to the integration of a fast F0.85 lens system with motorised focus and iris control, the images obtained are brighter and remarkably sharp, even for low-intensity signals.
One of the major advantages of the LAS-3000 is its dual software interface: Lite mode simplifies image capture for common applications (chemiluminescence, UV/blue fluorescence, digitisation), while Pro mode allows for advanced settings (custom selection of light source, filter, aperture, exposure time, etc.), ideal for experienced users or complex protocols. The system also allows the use of functions such as pixel binning (Standard, High, Super, Ultra), which increases detection sensitivity without compromising the final resolution thanks to software interpolation.
The device is equipped with a smart black box (IDX) with USB port, multiple sample trays (EPI, DIA, NP, DIA-UV), and comprehensive analysis software. It is compatible with various types of staining and detection methods, such as chemiluminescent membranes, coloured gels (CBB, silver), X-ray films and microplates.
In terms of image management, the LAS-3000 allows files to be saved in several formats (16-bit TIFF, 8-bit colour TIFF, Fuji IMG/INF format for quantitative analysis) and also offers the option of printing directly via a connected printer. Depending on experimental requirements, users can manually or automatically adjust exposure times, exposure type (precise, incremental, repeated or programmed), and acquisition resolution.
This system, although compact, stands out for its robustness, fast processing speed, and ability to capture very weak signals, making it a solution of choice for academic, hospital, or industrial laboratories looking for a reliable platform for their molecular imaging analyses.
