Thermo Cellomics ArrayScan VTI Live Cell Module: Comprehensive Live-Cell Analysis Solution
The Thermo Cellomics ArrayScan VTI Live Cell Module is engineered to meet the growing needs of live-cell imaging. By seamlessly integrating with the ArrayScan VTI HCS Reader, this module enhances its capabilities, allowing researchers to perform automated live-cell kinetic assays. The module’s ability to track cellular processes over extended periods provides invaluable insights into a wide range of cellular behaviors, such as migration, proliferation, apoptosis, and differentiation. This is vital for studies that require long-term, continuous observation of live cells.
Equipped with an incubation chamber, the module ensures that the cells remain in a controlled environment throughout the experiment, maintaining optimal conditions for cell viability. It offers precise control over temperature (ambient to 45°C), CO₂ concentration (0-10%), and humidity (greater than 90% relative humidity), closely replicating physiological conditions. This environmental regulation is essential for maintaining cell health during long-term studies, reducing variables that could affect the outcomes of the research.
The kinetic analysis software built into the module enables the automated extraction and analysis of images and data over time. It tracks individual cell identities, calculates motility, and measures various other dynamic cellular processes at both the cell and well levels. This automated system eliminates the need for manual intervention, increasing throughput and data consistency.
The module integrates the Zeiss™ Definite Focus system, an autofocus technology that ensures the focus remains stable throughout the experiment. This system is particularly important in long-term imaging, as it adjusts to any focus drift, ensuring that the images remain sharp and clear, which is critical for reliable data collection.
In addition, the module is compatible with various plate formats, including 96-well, 384-well, and 1536-well plates, providing flexibility for different experimental setups. Researchers can easily scale up their studies to handle high-throughput screenings without compromising the accuracy or quality of the data. The module also integrates with the HCS Studio Cell Analysis Software, offering a user-friendly interface for experiment setup, image acquisition, and data analysis. This software streamlines the entire process, allowing for efficient data management and visualization.
The Thermo Cellomics ArrayScan VTI Live Cell Module is designed with scalability in mind, ensuring that it can adapt to future technological advancements. This system is an invaluable tool for a wide range of applications, from basic cell biology research to more complex drug discovery and toxicology studies. Its robust performance, combined with its flexibility and ease of use, makes it a powerful addition to any laboratory.
