Mirante: Comprehensive Retinal Imaging with Advanced Modalities for Lesion Detection and Patient Follow-Up
The Mirante stands as a comprehensive imaging tool for retinal examination, consolidating all essential imaging modalities into a single product for daily use in fundus observation. It provides the flexibility to operate in ultra-large field mode, encompassing color photography, deconstruction into individual red/green/blue colors, infrared (IR) photography, autofluorescence (FAF-blue/FAF-green), retro mode, dynamic and static angiographies using fluorescein (FA) and indocyanine green (ICG), as well as OCT (Optical Coherence Tomography) and OCT-Angiography.
Utilizing a Laser Scanning Ophthalmoscope (LSO) that utilizes infrared, the Mirante delivers high-resolution, high-contrast images. The system employs eye tracking for patient eye movement management before and during OCT mode acquisition, ensuring accurate positioning of OCT and OCT-Angiography scans by considering the natural cyclotorsion of the human eye.
In the realm of LSO imaging of the fundus, the obtained images with an 89° normal field and a large field up to 163° are of high definition and premium contrast. The analysis of color photos and original red, green, and blue images directly from dedicated sensors enables detailed observation of fundus structures, facilitating the detection of lesions in retinal-choroidal pathologies.
Autofluorescence is employed for analyzing the pigmentary epithelium, offering two versions—one using green wavelength for macula visibility and the other using blue wavelength for optimal papilla observation, allowing adaptation to the studied pathology.
Dynamic or static injection angiography acquisitions using fluorescein and/or ICG enable observation of retinal and choroidal vascularization from early filling phases to late stages. Real-time infrared imaging aids in early alignment during injection, reducing information loss. The automatic gain setting, independent for fluorescein and ICG, limits signal saturation, confirming diagnoses through the detection of vascular lesions such as aneurysms, ischemia, and leaks.
The unique retro mode, specific to Mirante, utilizes infrared imaging to highlight deep layers of the retina, reinforcing the detection of fine lesions in these less accessible layers, including drusen lesions sometimes invisible with conventional imaging methods.
To extend the analysis zone to 163° and access the periphery, an ultra-large field adapter is employed. Tilting and rotating the upper part of the product enable observation up to the extreme periphery, and the reconstruction of various pictures provides a comprehensive view of the entire fundus up to the ora serrata.
In the domain of OCT and OCT-Angiography imaging, the Mirante is designed for specialized consultations, integrating advanced OCT functions such as HD mode, manual positioning of acquisition scans, Select mode and Rescan for additional examinations, and patient follow-up available immediately post-acquisition.
The LSO Tracking feature enables follow-up examinations under identical conditions, ensuring reliable comparative analysis, even on a single section. Up to 50 examinations can be compared over time for monitoring disease evolution and/or treatment effectiveness. Trend curves and manual event addition, such as the date of the first therapy use, enable efficient and personalized follow-up.
The Mirante includes an anterior segment adapter for corneal and filtration angle sections. AngioScan facilitates the analysis of retinal and choroidal vascularization, ensuring correct scan positioning with real-time retina tracking. Differentiated analyses are conducted on either the macula or optic nerve head, with segmentations adapted to the captured zone and density and vascular perfusion values provided for additional quantitative analysis.
With the combined display of OCT En-Face and OCT-Angiography, direct matching between tissue structure and vascularization is achieved. The Mirante's data analysis is facilitated through the NAVIS-EX software platform, managing the patient database for NIDEK imaging devices and equipped with viewers dedicated to Mirante results.
For LSO imaging analyses of the fundus, functionalities include multicolor/red/green/blue deconstruction, panoramic reconstruction, face-to-face right eye/left eye analysis, comparison between modalities with image resetting, and a patient follow-up tool. OCT and OCT-Angiography analyses encompass mapping of thicknesses for the macula and papilla, OCT En Face, OCT-Angiography with quantified analyses, 3D reconstruction, and patient follow-up.