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nanoACQUITY UPLC Separator

 The Waters Corporation nanoACQUITY UPLC system is a solution for nano-scale separations, ideal for biomarker discovery and proteomics applications. Designed to deliver exceptional sensitivity, resolution and reproducibility, this system is perfect for protein identification and characterisation. With a flow range of 200 nL/min to 100 µL/min and a maximum pressure of 10,000 psi, it enables accurate and reliable analyses. The nanoACQUITY UPLC is compatible with various mass spectrometers, making it an essential tool for research laboratories in life sciences, pharmaceuticals and biotechnology.



Description

nanoACQUITY UPLC System: The Ultimate Solution for Nano-Scale Separations

The nanoACQUITY UPLC system from Waters Corporation represents a major advance in ultra-high performance liquid chromatography (UPLC). Designed specifically for nano-scale separations, this system is ideal for applications in proteomics, metabolomics and biopharmaceutical analysis, where high sensitivity and resolution are essential for the detection and quantification of low-abundance biomolecules.

The nanoACQUITY UPLC stands out for its ability to deliver exceptional sensitivity, resolution and reproducibility. Thanks to its cutting-edge technology, it achieves unrivalled performance in protein identification and characterisation. The system is equipped with a binary solvent manager, a sample manager with integrated heating and trapping module, and an auxiliary solvent manager, making it a versatile and efficient tool for research laboratories.

One of the key features of the nanoACQUITY UPLC is its operational flow range, which extends from 200 nL/min to 100 µL/min without the need for flow splitting. This capability enables accurate and reproducible results, even for the most complex samples. In addition, the system can operate at a maximum pressure of 10,000 psi, allowing the use of longer, more efficient columns for high-resolution separations.

The nanoACQUITY UPLC is also designed to be compatible with a wide range of mass spectrometers, making it an essential tool for life science, pharmaceutical and biotechnology research laboratories. Whether for biomarker discovery, protein identification or biomolecule characterisation, this system offers a comprehensive and reliable solution for the most demanding applications.

The nanoACQUITY UPLC system from Waters Corporation is a versatile solution for nano-scale separations. With its exceptional sensitivity, resolution and reproducibility, it is ideal for applications in proteomics, metabolomics and biopharmaceutical analysis. Thanks to its compatibility with various mass spectrometers and its ability to operate at high pressures, it offers a comprehensive and reliable solution for the most demanding research laboratories.

Features

  • Exceptional sensitivity, resolution and reproducibility for proteomics, metabolomics and biopharmaceutical analysis applications.
  • Operating flow range from 200 nL/min to 100 µL/min without the need for flow splitting, enabling accurate and reproducible results.
  • Maximum pressure of 10,000 psi, allowing the use of longer, more efficient columns for high-resolution separations.
  • Compatibility with a wide range of mass spectrometers, making it an essential tool for life science, pharmaceutical and biotechnology research laboratories.
  • Binary solvent manager, sample manager with integrated heating and trapping module, and auxiliary solvent manager, offering increased versatility and efficiency.
  • Designed for nano-scale separations, ideal for biomarker discovery and protein identification.

Technical Details

  • Dimensions: 13.5″ W x 28″ D x 36.3″ H (34.3 cm x 71.1 cm x 92.2 cm)
  • Operating flow range: 200 nL/min to 100 µL/min
  • Maximum pressure: 10,000 psi
  • Fluid-wetted materials: 316 stainless steel, UHMWPE, sapphire, ruby, FEP, PTFE, ETFE, diamond-like coating, PEEK and PEEK alloys, titanium alloys, alumina ceramics, fused silica
  • Gradient accuracy: <0.25 min standard deviation for selected peptides, n=6
  • Operating temperature: 15 to 28 °C (58 to 82 °F)
  • Operating humidity: 20% to 80%, non-condensing
  • Power supply: 90 to 264V, 60Hz

Compatible Accessories

  • nanoACQUITY UPLC columns: Available with BEH, Atlantis and Symmetry chemistries in various sizes (75 µm to 300 µm internal diameter and 100 mm to 250 mm length).
  • Specialised trapping columns: For desalting and pre-concentrating larger sample volumes.
  • Additional modules: Heating and Trapping Module, Sample Manager, Binary Solvent Manager, Auxiliary Solvent Manager (optional), and FlexCart.

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