Agilent G1946-20174 Needle Holder – Technical Part for LC/MSD Systems in a Medical Setting
The G1946-20174 manufactured by Agilent is a needle holder for the 1100 series LC/MSD systems used in many medical and pharmaceutical laboratories. This component, installed in the spray chamber, is essential for the proper functioning of the nebuliser. It is responsible for mechanically holding the needle used for sample ionisation, a central process in mass spectrometry analysis.
In a biomedical context, where the accuracy and repeatability of analyses are crucial, the G1946-20174 holder ensures the stability of the needle during the critical phases of sampling. This stability is essential to ensure homogeneous ionisation, avoid signal fluctuations and preserve the quality of the data obtained. Misalignment or weak retention could lead to measurement deviations, compromising the validity of the results, particularly in biomarker analysis or diagnostic screening.
This holder is compatible with nebuliser needles specific to ESI technology (G1946-20177) or APCI (G1946-20097) nebuliser needles and fits into the complete nebulisation assembly with other parts such as the ferrule (G1946-20213) and O-ring seals. Its design is adapted to the technical constraints of laboratory environments, particularly those involving sensitive medical applications requiring reliability and robustness.
Choosing an original Agilent support, such as the G1946-20174, also extends the service life of other components in the system. By ensuring optimal needle positioning, it limits mechanical stress and prevents premature wear. It helps maintain the device's performance over the long term by facilitating maintenance and replacement of parts.
This component is therefore highly recommended in protocols requiring methodological rigour, such as clinical analyses, pharmacokinetic research or quality control of healthcare products. Reliable and designed to integrate seamlessly with Agilent instruments, the G1946-20174 is a strategic component for any LC/MSD installation used in the medical field.