The NexION 300 ICP-MS: a Powerful Analytical Platform for Elemental Detection in Human Health
PerkinElmer's NexION 300 ICP-MS is an essential tool in the field of elemental analysis for health and biological sciences. Designed to offer exceptional stability and reliability, this system enables extremely accurate quantification of trace metals, even in complex biological matrices such as blood, urine or tissue. It is particularly useful in biomonitoring, clinical toxicology and environmental analysis impacting human health.
Thanks to its patented Universal Cell Technology™, the NexION 300 offers three distinct operating modes: Standard (without gas), Collision (with kinetic energy discrimination), and Reaction (with quadrupole scanning). This system allows real-time adaptation to analytical needs, whether to eliminate polyatomic interference or achieve very low detection limits. This is particularly useful in the detection of elements such as lead, arsenic, selenium or vanadium, which are often involved in chronic diseases and metabolic disorders.
Its technical design incorporates a Triple Cone Interface coupled with a Quadrupole Ion Deflector, which ensures optimal ion beam definition while eliminating non-ionised materials. This device minimises cell fouling and allows continuous analysis without frequent cleaning, a real advantage for high-throughput laboratories.
The NexION 300 also features a dual-mode detection system (analogue and digital), ensuring a wide dynamic range and simultaneous detection of low and high concentration analytes. Its intuitive software interface, combined with automatic optimisation wizards such as SmartTune and Scheduler, simplifies routine operations, even for inexperienced users.
Its compact benchtop architecture, with no rear connections, optimises laboratory space while providing quick access to components. With its ability to integrate with liquid or ion chromatography systems, the NexION 300 is a complete solution for speciation analysis, identifying not only the quantity but also the chemical form of elements present in a sample. This feature is particularly valuable for assessing the toxicity or bioavailability of metals in the human body.
