PCX 5200: Performance and Precision for Post-Column Analysis
The PCX 5200 from Pickering Laboratories is a high-precision post-column derivatization instrument designed to enhance the detection and quantification of analytical compounds that are difficult to identify using HPLC alone. It enables a chemical reaction to be added to samples exiting the column, providing them with increased detectable properties, such as enhanced fluorescence or UV/VIS absorption.
The PCX 5200 is based on a simple yet effective concept: by mixing the effluent from the HPLC system with a specific reagent, it enables a post-column reaction that amplifies the detection of target analytes. Its heated reactor ensures that the chemical reaction achieves optimal yield while minimizing chromatographic peak dispersion.
Reagent stability is essential to ensure reliable results over long analysis durations. The PCX 5200 preserves reaction conditions by maintaining a uniform flow rate and preventing the formation of precipitates that could clog liquid circuits.
The device is designed for high durability and to minimize cross-contamination risks. Its thermostatic column oven ensures a controlled environment for temperature-sensitive analytes, while its reagent delivery pump provides a stable and reproducible flow rate.
For added safety, an overpressure protection system is integrated. In case of pressure drop or HPLC system shutdown, the PCX 5200 automatically cuts off reagent supply to prevent contamination of the analytical column.
The PCX 5200 is used in various analytical applications, including:
- Pesticide analysis (glufosinate, glyphosate, carbamates)
- Amino acid quantification
- Environmental contaminant monitoring
- Polyamine and diquat analysis
Compatible with different UV/VIS or fluorescence detectors, it seamlessly integrates into any modern HPLC system.
The PCX 5200 from Pickering Laboratories is an essential tool for laboratories looking to optimize their post-column chromatographic analyses, ensuring unmatched selectivity and sensitivity.
