High-Performance Flash Purification System puriFlash 430
The puriFlash 430 is the first system designed to support the ultra-performance flash purification (UPFP) concept. Recommended for laboratory applications and purification routines, this system allows the use of flash chromatography columns or cartridges up to F300 format. The puriFlash 430 is compatible with 15 µm silica columns, offering great flexibility for various purification applications.
The intelligent modular design of the puriFlash 430 allows for exceptional adaptability to meet changing purification requirements. Users can upgrade the system at any time to include higher pressure or higher flow pumps, additional detectors (ELSD, RI, MS) or additional manifolds. External fluid connections, including check valves and pump seals, are easily accessible to the end user, simplifying maintenance and upgrades.
The puriFlash 430 is equipped with a quaternary gradient HPLC pump with a flow rate of 200 ml/min and a maximum pressure of 30 bar. This pump is designed to provide years of continuous service with minimal maintenance. The pump's low dead volume allows for shallow, reproducible gradients without the need for pre-mixing solvents. Annual maintenance can be carried out in a matter of minutes by simply replacing the pump seals and check valves.
The system also features a dual wavelength UV detector with a detection range of 200 to 600 nm, as well as spectral view and purity confirmation. A second detection channel is available for adding an extended UV detector (190–840 nm), ELSD, or a simple quadrupole APCI mass spectrometer.
The puriFlash 430 is compatible with Interchim® software version 5.0, which offers a customisable user interface to manage the entire purification process, from method creation to the final report. The software allows user profiles to be defined, passwords to be managed, and report formats to be customised. Unique features of the software include TLC to Flash transposition, automatic gradient optimisation, intelligent continuous mode, dual trigger collection, timed automatic shutdown, and air purge.
The system is designed to save valuable space in laboratory fume hoods and can be placed on a bench with the option of a fraction collection enclosure. The fraction collector includes 4 racks for 176 x 18 mm tubes, and the system is equipped with a solvent-resistant keypad, a 10.5-inch touchscreen, 4 USB ports, and is Ethernet-ready.
The puriFlash 430 is a high-performance, flexible and easy-to-use flash purification system designed to meet the needs of modern laboratories for routine and laboratory-scale purification.
