JLA-10.500 : High-capacity performance for precise biological separation
The JLA-10.500 fixed-angle rotor by Beckman Coulter is a high-performance lab component specifically engineered for use with Avanti J and J2 series centrifuges, excluding JXN-30 and J-21 models. It offers an optimal combination of volume capacity, mechanical strength, and sedimentation efficiency thanks to an intelligent design that balances lightness with durability. Constructed from anodized aluminum and equipped with removable canisters made of carbon fiber epoxy composite, this rotor delivers excellent centrifugal performance for a variety of biological applications, including the clarification of physiological fluids, cell harvesting, viral concentration, and subcellular fractionation. Each of its six canisters holds up to 500 mL, for a total capacity of 3 liters per run, enabling the processing of large sample volumes in a single cycle while ensuring consistent and secure sample separation. Operating at a fixed angle of 20 degrees, the JLA-10.500 ensures efficient sedimentation while minimizing disruption of the pellet.
Its total capacity of 3 liters, distributed across six 500 mL canisters, enhances productivity by reducing the number of runs required for large-scale protocols. The rotor body, made of anodized aluminum, is both lightweight and corrosion-resistant, while the canisters—crafted from high-strength carbon fiber composite—offer excellent resistance to stress and deformation. This material choice significantly reduces the overall rotor weight by approximately 30% compared to all-metal equivalents, making handling easier and improving energy efficiency during acceleration and deceleration cycles.
The JLA-10.500 is rated for a maximum speed of 10,000 RPM, producing a relative centrifugal field (RCF) of up to 18,600 × g. For maximum sample safety and operator protection, each canister features a secure closure system with an internal O-ring that provides secondary containment in the event of tube failure. This sealing system has been tested for the containment of microbiological aerosols under standard biosafety protocols. Balanced loading is essential for stable performance, with opposing canisters required to be within 10 grams of each other to maintain dynamic equilibrium during operation.
To support maintenance and daily use, the rotor and its components can be cleaned using non-corrosive detergents and are compatible with sterilization procedures such as autoclaving at 121°C for 30 minutes. The rotor is also equipped with embedded magnets for automatic rotor recognition in Avanti J-E centrifuges, ensuring proper configuration and eliminating the risk of speed mismatch. It is compatible with a wide range of tubes and bottles via dedicated adapters, providing great versatility for multiple laboratory workflows. With its thoughtful design, consistent performance, and proven reliability, the JLA-10.500 rotor is an essential tool for laboratories seeking safe, efficient, and high-volume centrifugation.
