Slide scanner InnoScan 1100 AL

InnoScan 1100 AL: Ultra-High Resolution Fluorescence Microarray Scanner

The InnoScan 1100 AL stands out as one of the most microarray scanners on the market, offering unparalleled resolution of up to 0.5 µm/pixel, equivalent to a 20x objective. This scanner is designed to deliver high-quality images thanks to its real-time autofocus system and confocal PMT detection, enabling detailed microarray analysis.

Easy automation is one of the InnoScan 1100 AL's strengths. Thanks to its user-friendly image acquisition software and 24-slide autoloader, it allows for fully automated scanning of 24 slides at a time. This feature is particularly useful for laboratories requiring fast and efficient processing of large volumes of data.

The InnoScan 1100 AL is also capable of reading standard microscope slides with various substrates, including cells, tissues, proteins, DNA, glycans, and peptides. With three excitation channels, it offers multiplexing capabilities, allowing the simultaneous analysis of multiple samples or markers on the same slide. This makes it an ideal tool for reading tri-color microarrays as well as for cell and tissue studies.

In terms of performance, the InnoScan 1100 AL is equipped with three excitation lasers (488, 532, and 635 nm) coupled with three highly sensitive photomultiplier tubes (PMTs). These PMTs are linear across the entire dynamic range, facilitating gain adjustment for optimal fluorescence levels without saturation. Additionally, the XDR (Extended Dynamic Range) mode offers a 6-log dynamic range, maximizing the detection of weak signals while avoiding saturated spots. The InnoScan 1100 AL is renowned for its excellent photometric properties, particularly in terms of sensitivity and signal-to-noise ratio. It is ideally suited for a wide range of applications, including cell microarrays, tissue immunofluorescence, three-color microarrays, and high-density microarrays. Used in diverse fields such as cell and tissue imaging, the food industry, glycomics, pharmaceuticals, proteomics, and biomarker and disease stratification, the InnoScan 1100 AL is a versatile and powerful tool for modern laboratories.

• Weight: 35 kg (77.16 lbs)
• Dimensions: 33 x 66 x 44 cm³ (13” x 26” x 17.3”)
• Resolution: 0.5-40 µm/pixel
• Excitation Wavelengths: 488 nm, 532 nm, 635 nm
• Compatible Fluorophores: 488 nm: Cy2, Alexa488, FITC; 532 nm: Cy3, Alexa 546, Alexa 555, Sytox Orange; 635 nm: Cy5, Alexa 647, Alexa 660, Draq5
• Compatible Slides: Standard microscope slides according to ISO 8037-1, 25-26 x 75-76 mm² / 1” x 3”; thickness: 0.9 - 1.2 mm
• Maximum Scanning Area: 22 x 74 mm²
• Focus: Automatic or manual
• Detection: Analog PMT confocal detection
• PMT gain: Linear from 0 to 100% (0.1 steps from 0.1 to 1% and 1 from 1 to 100%)
• Scanning mode: Simultaneous or sequential
• Scanning speed: 20 to 35 lines/sec (25 lines/sec max for a pixel size of 0.5 µm)
• Scanning time: 3.5 minutes to scan a full slide at 10 µm/pixel and 3 colors; 10.5 minutes for a 22 x 22 mm² area at 1 µm/pixel and 3 colors
• Interface: Ethernet
• Barcode reader: Yes
• Image processing software: Mapix
• Image file format: 16-bit and 20-bit TIFF