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Tangential filtration system Sartoflow Smart


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The Sartoflow® Smart is a modular and flexible crossflow filtration (TFF) system designed for ultrafiltration and diafiltration applications. Ideal for the purification of vaccines, monoclonal antibodies, and recombinant proteins, it is ideally suited for laboratory environments for process development and clinical trials, as well as for small-batch cGMP production.

Description

Sartoflow® Smart: Modular TFF System for High-Precision Purification


The Sartoflow® Smart is a small-scale cross-flow filtration (TFF) system designed for benchtop use. This modular and flexible system is optimized for ultrafiltration and diafiltration applications, essential in many downstream processes such as the purification of vaccines, monoclonal antibodies, and recombinant proteins. Thanks to its versatile design, the Sartoflow® Smart is ideal for laboratory environments, where it facilitates process development and clinical trials. Furthermore, it is suitable for small-batch cGMP production, ensuring compliance with the strictest quality standards.

The system stands out for its exceptional flexibility, capable of handling membrane areas ranging from 50 cm² to 0.14 m², with numerous customization options available. These include an automated retentate valve, an external diafiltration pump, a Sartocon® Slice 50 cassette holder, and sensors for pH, conductivity, and temperature. These features allow for precise adaptation to each user's specific needs, ensuring optimal performance in various applications.

The Sartoflow® Smart's intuitive user interface allows operators to easily launch predefined production sequences for concentration, diafiltration, rinsing, filling, drainage, and backwash steps. This advanced automation ensures data continuity and reproducibility, essential for process development and optimization. Furthermore, the system is designed to allow full transfer of process data to large-scale systems, facilitating scale-up and downscaling studies.

The Sartoflow® Smart is also notable for its low minimum sample and recirculation volumes, making it ideal for small process batches. With easy access to data and a high level of automation, this system is an indispensable tool for developers looking to establish and refine process parameters. Finally, its compatibility with cGMP environments makes it a preferred choice for applications requiring strict regulatory compliance.

Features

  • Exceptional flexibility for membrane areas from 50 cm² to 0.14 m².
  • Intuitive user interface with predefined production sequences.
  • Automation for data continuity and reproducibility.
  • Low minimum sample and recirculation volumes.
  • Compatibility with cGMP environments.
  • Complete process data transfer to large-scale systems.
  • Customization options to meet specific user needs.

Technical Details

  • Weight: ~35 kg (77 lbs.)
  • Dimensions: 602 × 440 × 610 mm
  • Membrane Area: 50 cm², 200 cm², 400 cm², 0.14 m²
  • Recirculation Vessel Volume: PSU vessel with agitator: 1 L, Single-use Flexboy® bags: 150 - 1,000 L
  • Flow Rate: 1–100 L/h @ 3 bar (43.5 psi)
  • Minimum Recirculation Volume: < 20 mL
  • Level of Automation: Semi-automated
  • Process Mode: Multi-purpose
  • cGMP Available: Yes
  • Maximum Pressure: 3 bar (43.5 psi)
  • Temperature Control: No, monitoring only
  • Tube ID: 1/8"
  • Connections: Luer-lock
  • Sensors: Pressure (online: feed, permeate, retentate), Conductivity, pH, Temperature (in PSU vessel)

Compatible Accessories

  • Automated retentate valve.
  • External diafiltration pump.
  • Sartocon® Slice 50 cassette holder.
  • Sensors for pH, conductivity, and temperature.
  • External permeate scale up to 64 kg.
  • Recirculation and/or permeate holder for Flexboy® bags.
  • IQ/OQ execution package.

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Logistics

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Warranty

Our 12/24-month warranty ensures the safety and reliability of your medical equipment throughout its lifespan.

Flexible Financing

Settle your medical equipment in up to 36 installments with our financing service or pay after delivery with Remma Facility.