Agilent G1379A: A High-Performance Vacuum Degasser for Optimal Chromatographic Analyses
The Agilent G1379A vacuum degasser is an essential component of high-performance liquid chromatography (HPLC) systems. It is designed to efficiently remove dissolved gases from the solvents used in the mobile phase, ensuring a continuous and homogeneous flow. This process is crucial for preventing the formation of air bubbles, which can cause flow disruptions, signal instability, or even analytical errors. With its optimized design and compatibility with Agilent’s 1100 series, the G1379A is a preferred choice for research laboratories, quality control facilities, and environmental, pharmaceutical, or food analysis applications.
In chromatography, the stability of the mobile phase flow is a fundamental parameter that directly influences the quality and repeatability of results. The presence of dissolved gases can lead to pressure fluctuations in the system, alter detector response, and compromise analyte separation. The G1379A ensures optimal degassing through its technology, which applies partial vacuum to tubular polymer membranes.
The device is equipped with four degassing channels, allowing simultaneous processing of multiple solvents. This feature is particularly advantageous for laboratories using solvent mixtures or performing gradient analyses. The efficiency of the degasser helps improve analysis reliability, extend the lifespan of chromatographic columns, and reduce equipment maintenance.
The G1379A uses a vacuum membrane degassing system, a cutting-edge technology that removes dissolved gases without altering the chemical composition of the solvents. Each channel of the degasser is fitted with a semi-permeable fluoropolymer membrane that allows gases to pass through while retaining liquids. A partial vacuum is generated inside the degassing chamber, facilitating the diffusion of dissolved gases out of the solvent.
This process is significantly more effective than traditional degassing methods such as ultrasonic degassing or helium sparging. Vacuum degassing greatly reduces pressure fluctuations in the HPLC system, ensuring a smooth and stable flow. It effectively prevents air bubble formation in pumps and detectors, avoiding signal disturbances. Additionally, it decreases the maintenance required for pumps and chromatographic columns, optimizing the longevity of the equipment.
The G1379A is designed to support a maximum flow rate of 5 mL/min per channel while maintaining optimal degassing efficiency. Beyond this threshold, between 5 and 10 mL/min, degassing efficiency may be reduced, though the device continues to operate with good performance.
In terms of connectivity and power supply, the device is designed to operate within a wide voltage range of 100 to 120 V or 220 to 240 V AC ± 10 %, and a line frequency of 50 or 60 Hz ± 5 %, making it compatible with electrical standards in many countries. It is also built to function in various environmental conditions, supporting an ambient operating temperature of 4 to 55°C, as well as humidity below 95 % between 25 and 40°C, without condensation.
The Agilent G1379A meets international safety and performance standards, ensuring reliable and secure use in all types of laboratories. It complies with CEI, CSA, and UL certifications and adheres to installation category II, pollution degree 2 requirements.
With its robust design, compatibility with Agilent’s 1100 series, and advanced technology, the G1379A is a strategic investment for laboratories seeking to improve the reliability and efficiency of their chromatographic analyses.
